Team of Lecturers
Marco Mazzotti has been professor of process engineering at ETH Zurich since May 1997 (associate until March 2001 and full professor thereafter). He holds a Laurea (M.S., 1984) and a Ph.D. (1993), both in Chemical Engineering, from the Politecnico di Milano, Italy. Before joining ETH Zurich, he had worked for IBM Italy (1985-1987) and Montefluos (1988-1990), and had been assistant professor at the Politecnico di Milano (1994-1997).
Marco Mazzotti has been coordinating lead author of the IPCC Special Report on Carbon Dioxide Capture and Storage (2002-2005). He is the chairman of the EFCE Working Party on Crystallization and past-President of the International Adsorption Society (2010-2013). He was the chair of the 9th International Conference on Fundamentals of Adsorption FOA9 (Italy, May 20-25, 2007) and of the 18th International Symposium on Industrial Crystallization (Switzerland, September 15-16, 2011).
Professor Mazzotti’s research activity deals with adsorption based separations and chromatography, and with crystallization and precipitation processes. The application areas of interest are the purification of biopharmaceuticals and the development of carbon dioxide capture and storage systems.
Professor Peter Gardner
Peter Gardner is a Professor of Analytical and Biomedical Spectroscopy and a fellow of the Royal Society of Chemistry. He obtained a Ph.D. in surface vibrational spectroscopy in 1988 from the University of East Anglia. This was followed by postdoctoral appointments at the Fritz Haber Institute (MPG) in Berlin and Chemistry Department at the University of Cambridge where he was involved in the development of surface infrared spectroscopic methods. In 1994 he was appointed as a Lecturer in Chemistry Department at UMIST and he was promoted to Senior Lecturer in 2000 and Reader in 2010. In 2004, with the formation of the University of Manchester he joined the School of Chemical Engineering and Analytical Science.
Since 2000 he has built a successful biomedical spectroscopy group, which has focused on using vibrational spectroscopy in the diagnosis of prostate and other cancers. His group also has a keen interest in understanding the fundamental caused of spectroscopic discrimination and separating biochemical and physical spectral influences. Recently his group have been interested in unravelling spectral artefacts associated with single cell spectra. His group have developed scattering correction algorithms In collaboration with groups in Dublin and Norway that are now being used worldwide.
Professor Philip Martin
Philip Martin is a Professor in the School of Chemical Engineering and Analytical Science. He has a first degree in Chemistry from the University of Oxford and a PhD from Cambridge in physical chemistry in the group of Professor Paul Davies. Following this he held a Royal Society European Fellowship at the Universite de Paris-Sud/CNRS in Orsay in the group of Guy Guelachvili. Following this he spent three years in the group of Professor John Maier FRS at the University of Basel in Switzerland where he worked on laser spectroscopy of free radicals and molecular ions. In 1993 he took up a position at the University of Huddersfield where he developed techniques in applied spectroscopy and environmental technology using novel laser sources.
He set up a spin-off company, TDL Sensors Ltd. in 2000 and then moved to Manchester in 2002. In the School he has held roles of Director of Research, Director of Post-Graduate Research and Director of Taught Postgraduate. He has research labs in the Mill Building and Photon Science Institute. Recently he has become a Fellow of the Royal Society of Chemistry and also a Fellow of the Institute of Physics
The main area of research is into the development of novel techniques for process and environmental analysis. The aim is to develop in situ, non-invasive optical techniques to extract process information such as chemical species concentrations, temperature, pressure and mass flows.
Dr Elena Simone
Elena Simone graduated with an MSc in Chemical Engineering from the University of Pisa (Italy) and then moved to Loughborough University (UK) to study for a PhD in the Department of Chemical Engineering. After obtaining her doctorate degree she stayed in the same institution for a postdoc. Elena joined the School of Food Science and Nutrition at the University of Leeds in September 2016 as Lecturer in Remote Sensing.
Her research interests include:
- Understanding the phenomena of polymorphism, nucleation and crystal growth of pharmaceuticals and food crystals (e.g. fats, sugars) using on-line, in situ, analytical techniques as well as off-line solid state characterisation;
- Developing strategies to effectively control crystal size, shape and polymorphism during crystallisation processes combining experimental and modelling work (Population Balance Equations);
- Application of Process Analytical Technology (PAT) tools and Quality by Design (QbD) in the food industry.
Dr Thomas Vetter
Thomas Vetter has been a lecturer at the School of Chemical Engineering and Analytical Science since September 2014. He holds a PhD in process engineering (2012), an MSc in Chemical- and Bioengineering (2008), and a BSc in Chemical Engineering (2007); all from ETH Zurich. He received an Eli Lilly Innovation Fellowship Award (LIFA) for his postdoc, which was co-located between the Eli Lilly headquarters in Indianapolis and UC Santa Barbara. Since August 2016, he is a Royal Academy of Engineering research fellow.
Dr Vetter’s research interests lie in the design of combined reaction/crystallization systems with the ultimate goal of obtaining an intensified and globally optimal process that outperforms the individually optimized unit operations.
Dr Alex Henderson
Alex Henderson holds a BSc in Chemistry from UMIST (1988) and a PhD in photoelectron spectroscopy of small metallic particles (UMIST, 1996).
Dr Henderson’s research interests lie in data reduction, working mainly with the results from IR (infrared spectroscopy) and ToF-SIMS (time of flight secondary ion mass spectrometry) experiments in cell chemistry. Chemometric and cheminformatic approaches are applied to spectra, 2D chemical images and 3D chemical hypercubes to understand the complex chemistries involved in cell structure, metabolism and drug interaction. Work carried out in parallel aims to develop visualisation tools for chemists and biologists working in this area. In addition to his work in the FTIR field I also work on ToFSIMS data of tissue and inorganic materials as a member of John Vickerman’s research group.
Professor Roger Davey
Professor Roger Davey has earned an international reputation in the field of materials science related to crystalline pharmaceutical active ingredients. His fundamental scientific work has encompassed key aspects of the production, formulation and discovery of such materials including crystal chemistry and morphology, crystallisation and polymorphism. Over his 40 year career he has worked for ICI, AstraZeneca and joined the University of Manchester in 1994.
Roger's research activities involve the application of crystal chemistry to the design of inorganic and molecular materials as well as surface active molecules. His current research interests continue to develop the field and include the preparation of materials with controlled crystal structure and morphology; structure property relationships in molecular salts and co-crystals and the study of crystal nucleation
Dr Nima Yazdanpanah
Nima Yazdanpanah is a research scientist in the US Food and Drug Administration. His area of expertise covers mathematical modeling, particulate matters, process design, and advanced manufacturing. Prior to joining FDA, Nima was a postdoctoral research associate at MIT, Department of Chemical Engineering, and Novartis-MIT Center for Continuous Manufacturing. He received his PhD from The University of Sydney, Australia. He has worked for six years in industry for R&D and Process Design sections.
Nima has received multiple national and international awards. He has published numerous journal papers and book chapters, holds two patent applications, and the editor of the Handbook of Continuous Crystallization (under publication by the Royal Society of Chemistry). He is a senior member of the American Institute of Chemical Engineering (AIChE). He serves on several review panels and advisory committees.
Dr Mei Lee
Dr Mei Lee first research project as an undergraduate student was on the effect of organic impurities on the crystallization of gibbsite, in 1988!. This was quickly followed by several placements and roles in the mineral industry on crystallization which culminated in a PhD on mechanism of crystal growth. After over 8 years working on crystallization in the mineral industry, Dr Lee left Australia and embarked on a Postdoc at Sanofi in Montpellier, France where I used the in-situ microscopy techniques, developed during my PhD and transferred it to crystallization in pharmaceutical industry. Upon completion of her Postdoc, She gained employment at GlaxoWellcome, now GlaxoSmithKline, where she have been for the last 18 years. In this time,she have worked on numerous crystallization projects across the development phases as well as on commercial products, batch and continuous crystallizations and transferred processes to our pilot plant and commercial plants.
Dr Lee research interests lie in the industrial aspects of crystallization and polymorphism with the focus on using analyticals tools for optimization of unit operations during drug development in pharmaceutical industry (e.g. reduce production cycling time, prevent rejection of batches, increase automation and control and improve energy and material use)
Dr David Wilson
Dr David Wilson has 12 years experience in the pharmaceutical industry. During that time he has worked in various capacities including: material scientist, formulator, process engineer and most recently as a particle engineer. His expertise includes both drug product and drug substance development. He has a PhD from Imperial College, London and is a chartered Chemical Engineer.
Particle size and shape measurement is of fundamental importance to the chemical engineer working in the pharmaceutical industry. His research interests include latest approaches to measurement, data analysis and use of these properties in drug product development.